1. Add two new Buttons:

2. Select the first button and go into the layout editor:

3. Create a new button layout:

4. Change the bitmaps for the released and pressed state and press the apply button to assign this new layout to the selected button:

5. Select the second button and repeat steps 1-4

Now you have created two new button layouts and can assign these to new created or existing buttons.

More How- To’s:
How to create new button Layouts
How to create new Macros
How to call external applications
How to assign device keys